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Characterization of jet formation and flow field produced by tandem bubbles
Author(s) -
Chen Yang,
Andrew S. Koff,
Fang Yuan,
Pei Zhong,
Chao-Tsung Hsiao,
Georges L. Chahine
Publication year - 2017
Publication title -
aip conference proceedings
Language(s) - English
Resource type - Conference proceedings
eISSN - 1551-7616
pISSN - 0094-243X
DOI - 10.1063/1.4977637
Subject(s) - bubble , tandem , jet (fluid) , mechanics , microfluidics , flow (mathematics) , materials science , characterization (materials science) , physics , nanotechnology , composite material
Tandem bubble (TB) interactions have been shown to produce directional jets that can be used to create membrane poration on single cells. Jet speed and associated flow field produced around the TB have been postulated to play an important role in TB–induced bioeffects. In this study, dynamics of tandem bubble interaction in a microfluidic channel (25 µm in height) was analyzed by high-speed imaging and simulated using 3DYNAFS-BEM© (DYNAFLOW, INC.). The results suggest that jet size and geometry are primarily controlled by the maximum diameter of the first bubble (D1) while jet speed is about linearly correlated with maximum diameter of the second bubble (D2).

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