Fabrication of three-dimensional micro-nanofiber structures by a novel solution blow spinning device | Zendy

Feng Liang | Zendy; Feiyu Fang | Zendy; Jun Zeng | Zendy; Zhifeng Wang | Zendy; Weijun Ou | Zendy; Xindu Chen | Zendy; Peixuan Wu | Zendy; Han Wang | Zendy; Lin Zhang | Zendy

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Fabrication of three-dimensional micro-nanofiber structures by a novel solution blow spinning device

Author(s) -

Feng Liang,

Feiyu Fang,

Jun Zeng,

Zhifeng Wang,

Weijun Ou,

Xindu Chen,

Peixuan Wu,

Han Wang,

Lin Zhang

Publication year - 2017

Publication title -

aip advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.421

H-Index - 58

ISSN - 2158-3226

DOI - 10.1063/1.4973719

Subject(s) - fabrication , spinning , materials science , porosity , nanofiber , volatility (finance) , fiber , composite material , volumetric flow rate , solvent , nanotechnology , chemistry , mechanics , medicine , alternative medicine , physics , organic chemistry , pathology , financial economics , economics

The fabrication of three-dimensional scaffolds has attracted more attention in tissue engineering. The purpose of this study is to explore a new method for the fabrication of three-dimensional micro-nanofiber structures by combining solution blow spinning and rotating collector. In this study, we successfully fabricated fibers with a minimum diameter of 200 nm and a three-dimensional structure with a maximum porosity of 89.9%. At the same time, the influence of various parameters such as the solvent volatility, the shape of the collector, the feed rate of the solution and the applied gas pressure were studied. It is found that solvent volatility has large effect on the formation of the three-dimensional shape of the structure. The shape of the collector affects the porosity and fiber distribution of the three-dimensional structure. The fiber diameter and fiber uniformity can be controlled by adjusting the solution feed rate and the applied gas pressure. It is feasible to fabricate high-quality three-dimensional micro-nanofiber structure by this new method, which has great potential in tissue engineering

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