Basilar membrane and reticular lamina motion in a multi-scale finite element model of the mouse cochlea | Zendy

Joris Soons | Zendy; Joris Dirckx | Zendy; Charles R. Steele | Zendy; Sunil Puria | Zendy

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Basilar membrane and reticular lamina motion in a multi-scale finite element model of the mouse cochlea

Author(s) -

Joris Soons,

Joris Dirckx,

Charles R. Steele,

Sunil Puria

Publication year - 2015

Publication title -

aip conference proceedings

Language(s) - English

Resource type - Conference proceedings

SCImago Journal Rank - 0.177

H-Index - 75

eISSN - 1551-7616

pISSN - 0094-243X

DOI - 10.1063/1.4939351

Subject(s) - basilar membrane , reticular connective tissue , cochlea , tectorial membrane , physics , anatomy , finite element method , hair cell , stereocilia (inner ear) , biophysics , biology , thermodynamics

A multi-scale finite element (FE) model of the mouse cochlea, based on its anatomy and material properties is presented. The important feature in the model is a lattice of 400 Y-shaped structures in the longitudinal direction, each formed by Deiters cells, phalangeal processes and outer hair cells (OHC). OHC somatic motility is modeled by an expansion force proportional to the shear on the stereocilia, which in turn is proportional to the pressure difference between the scala vestibule and scala tympani. Basilar membrane (BM) and reticular lamina (RL) velocity compare qualitatively very well with recent in vivo measurements in guinea pig [2]. Compared to the BM, the RL is shown to have higher amplification and a shift to higher frequencies. This comes naturally from the realistic Y-shaped cell organization without tectorial membrane tuning.

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