Use of triple correlations for the sign determinations of expansion coefficients of symmetric approximations to the diffraction volumes of regular viruses | Zendy

H. C. Poon | Zendy; D. K. Saldin | Zendy

Open Access

Use of triple correlations for the sign determinations of expansion coefficients of symmetric approximations to the diffraction volumes of regular viruses

Author(s) -

H. C. Poon,

D. K. Saldin

Publication year - 2015

Publication title -

structural dynamics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.415

H-Index - 29

ISSN - 2329-7778

DOI - 10.1063/1.4922476

Subject(s) - homogeneous space , diffraction , physics , laser , crystallization , point source , perturbation (astronomy) , perturbation theory (quantum mechanics) , electron , triple point , sign (mathematics) , x ray crystallography , mathematics , mathematical analysis , optics , quantum mechanics , geometry , thermodynamics

An X-ray free electron laser is a new source of x-rays some 10 × 109 times brighter than any previous X-ray source, giving rise to the possibility of structure determination of individual biological particles without crystallization. Some of the earliest samples used in the X-ray free electron laser are viruses because they are about the largest of reproducible bioparticles. We show how common virus near-symmetries can be exploited to find a first approximation to their structures to give a starting point for a perturbation approach to determine their structures

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