Open AccessGadolinia nanofibers as a multimodal bioimaging and potential radiation therapy agent
Author(s) -
Alexander M. Grishin,
Abolfazl Jalalian,
M. I. Tsindlekht
Publication year - 2015
Publication title -
aip advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 58
ISSN - 2158-3226
DOI - 10.1063/1.4919810
Subject(s) - nanofiber , materials science , gadolinium , superparamagnetism , electrospinning , calcination , photoluminescence , proton , chemical engineering , nuclear magnetic resonance , nanotechnology , composite material , polymer , magnetization , chemistry , optoelectronics , organic chemistry , catalysis , physics , quantum mechanics , magnetic field , engineering , metallurgy
Continuous bead-free C-type cubic gadolinium oxide (Gd2O3) nanofibers 20-30 μm long and 40-100 nm in diameter were sintered by sol-gel calcination assisted electrospinning technique. Dipole-dipole interaction of neighboring Gd3+ ions in nanofibers with large length-to-diameter aspect ratio results in some kind of superparamagnetic behavior: fibers are magnetized twice stronger than Gd2O3 powder. Being compared with commercial Gd-DTPA/Magnevist®, Gd2O3 diethyleneglycol-coated (Gd2O3-DEG) fibers show high 1/T1 and 1/T2 proton relaxivities. Intense room temperature photoluminescence, high NMR relaxivity and high neutron scattering cross-section of 157Gd nucleus promise to integrate Gd2O3 fibers for multimodal bioimaging and neutron capture therapy