Rheological techniques for determining degradation of polylactic acid in bioresorbable medical polymer systems
Author(s) -
Gabriel Y. H. Choong,
Andrew J. Parsons,
David M. Grant,
Davide S. A. De Focatiis
Publication year - 2015
Publication title -
aip conference proceedings
Language(s) - English
Resource type - Conference proceedings
eISSN - 1551-7616
pISSN - 0094-243X
DOI - 10.1063/1.4918523
Subject(s) - rheology , polylactic acid , polystyrene , materials science , polymer , polycarbonate , molar mass , context (archaeology) , degradation (telecommunications) , nanocomposite , composite material , chemical engineering , computer science , geology , paleontology , telecommunications , engineering
A method developed in the 1980s for the conversion of linear rheological data to molar mass distribution is revisited in the context of degradable polymers. The method is first applied using linear rheology for a linear polystyrene, for which all conversion parameters are known. A proof of principle is then carried out on four polycarbonate grades. Finally, preliminary results are shown on degradable polylactides. The application of this method to degrading polymer systems, and to systems containing nanofillers, is also discussed. This work forms part of a wider study of bioresorbable nanocomposites using polylactides, novel hydroxyapatite nanoparticles and tailored dispersants for medical applications.
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