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Comment on “Steady-state fluctuations of a genetic feedback loop: An exact solution” [J. Chem. Phys. 137, 035104 (2012)]
Author(s) -
Guilherme C. P. Innocentini,
Alexandre F. Ramos,
José Eduardo Martinho Hornos
Publication year - 2015
Publication title -
the journal of chemical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 357
eISSN - 1089-7690
pISSN - 0021-9606
DOI - 10.1063/1.4905217
Subject(s) - steady state (chemistry) , normalization (sociology) , exact solutions in general relativity , constant (computer programming) , physics , differential equation , mathematics , statistical physics , mathematical physics , quantum mechanics , computer science , chemistry , sociology , anthropology , programming language
The comment presents the complete steady state solution of the model introduced on ”Steady-state fluctuations of a genetic feedback loop: An exact solution” [Grima et al. J. Chem. Phys. 137, 035104 (2012)]. A closed form for the normalization constant is obtained and hence the explicit calculation of the moments as functions of the parameters is possible. We discuss the meaning of an exact solution to a differential equation and the construction of a model to the understanding of a phenomenon.

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