Adhesive characteristics of low dimensional carbon nanomaterial on actin | Zendy

Tong Li | Zendy; Adekunle Oloyede | Zendy; Yuantong Gu | Zendy

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Adhesive characteristics of low dimensional carbon nanomaterial on actin

Author(s) -

Tong Li,

Adekunle Oloyede,

Yuantong Gu

Publication year - 2014

Publication title -

applied physics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.182

H-Index - 442

eISSN - 1077-3118

pISSN - 0003-6951

DOI - 10.1063/1.4862200

Subject(s) - nanomaterials , graphene , nanotechnology , materials science , monolayer , carbon fibers , actin , actin cytoskeleton , oxide , chemistry , cytoskeleton , composite material , cell , composite number , biochemistry , metallurgy

The biosafety of carbon nanomaterial needs to be critically evaluated with both experimental and theoretical validations before extensive biomedical applications. In this letter, we present an analysis of the binding ability of two dimensional monolayer carbon nanomaterial on actin by molecular simulation to understand their adhesive characteristics on F-actin cytoskeleton. The modelling results indicate that the positively charged carbon nanomaterial has higher binding stability on actin. Compared to crystalline graphene, graphene oxide shows higher binding influence on actin when carrying positive surface charge. This theoretical investigation provides insights into the sensitivity of actin-related cellular activities on carbon nanomaterial

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