Open AccessPhysics of cancer propagation: A game theory perspective
Author(s) -
Chris Cleveland,
David Liao,
Robert H. Austin
Publication year - 2012
Publication title -
aip advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 58
ISSN - 2158-3226
DOI - 10.1063/1.3699043
Subject(s) - perspective (graphical) , competition (biology) , dynamics (music) , game theory , stress (linguistics) , cancer , simple (philosophy) , computer science , cognitive science , biology , physics , microeconomics , psychology , economics , ecology , epistemology , artificial intelligence , genetics , linguistics , philosophy , acoustics
This is a theoretical paper which examines at a game theoretical perspective the dynamics of cooperators and cheater cells under metabolic stress conditions and high spatial heterogeneity. Although the ultimate aim of this work is to understand the dynamics of cancer tumor evolution under stress, we use a simple bacterial model to gain fundamental insights into the progression of resistance to drugs under high competition and stress conditions
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