An integrated micro-chip for rapid detection of magnetic particles
Author(s) -
Chinthaka P. Gooneratne,
Liang Cai,
Ioanna Giouroudi,
Jǘrgen Kosel
Publication year - 2012
Publication title -
journal of applied physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.699
H-Index - 319
eISSN - 1089-7550
pISSN - 0021-8979
DOI - 10.1063/1.3678303
Subject(s) - wheatstone bridge , giant magnetoresistance , materials science , chip , fabrication , optoelectronics , nanotechnology , noise (video) , magnetoresistance , magnetic field , electrical engineering , computer science , physics , engineering , resistor , voltage , medicine , alternative medicine , pathology , quantum mechanics , artificial intelligence , image (mathematics)
This paper proposes an integrated micro-chip for the manipulation and detection of magnetic particles (MPs). A conducting ring structure is used to manipulate MPs toward giant magnetoresistance(GMR) sensing elements for rapid detection. The GMRsensor is fabricated in a horseshoe shape in order to detect the majority of MPs that are trapped around the conducting structure. The GMR sensing elements are connected in a Wheatstone bridge circuit topology for optimum noise suppression. Full fabrication details of the micro-chip, characterization of the GMRsensors, and experimental results with MPs are presented in this paper. Experimental results showed that the micro-chip can detect MPs from low concentration samples after they were guided toward the GMRsensors by applying current to the conducting ring structure
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