Atomic force microscopy of electrospun organic-inorganic lipid nanofibers | Zendy

Jinhong Zhang | Zendy; Celine Cohn | Zendy; Weiguo Qiu | Zendy; Zhengbao Zha | Zendy; Zhifei Dai | Zendy; Xiaoyi Wu | Zendy

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Atomic force microscopy of electrospun organic-inorganic lipid nanofibers

Author(s) -

Jinhong Zhang,

Celine Cohn,

Weiguo Qiu,

Zhengbao Zha,

Zhifei Dai,

Xiaoyi Wu

Publication year - 2011

Publication title -

applied physics letters

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.182

H-Index - 442

eISSN - 1077-3118

pISSN - 0003-6951

DOI - 10.1063/1.3635783

Subject(s) - nanoindentation , nanofiber , atomic force microscopy , silane , materials science , nanostructure , chemical engineering , nanotechnology , elastic modulus , chemistry , composite material , engineering

An organic-inorganic hybridization strategy has been proposed to synthesize polymerizable lipid-based materials for the creation of highly stable lipid-mimetic nanostructures. We employ atomic force microscopy (AFM) to analyze the surface morphology and mechanical property of electrospun cholesteryl-succinyl silane (CSS) nanofibers. The AFM nanoindentation of the CSS nanofibers reveals elastic moduli of 55.3 ± 27.6 to 70.8 ± 35 MPa, which is significantly higher than the moduli of natural phospholipids and cholesterols. The study shows that organic-inorganic hybridization is useful in the design of highly stable lipid-based materials.

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