Stochastic protein production and time-dependent current fluctuations | Zendy

Mieke Gorissen | Zendy; Carlo Vanderzande | Zendy

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Stochastic protein production and time-dependent current fluctuations

Author(s) -

Mieke Gorissen,

Carlo Vanderzande

Publication year - 2011

Publication title -

aip conference proceedings

Language(s) - English

Resource type - Conference proceedings

SCImago Journal Rank - 0.177

H-Index - 75

eISSN - 1551-7616

pISSN - 0094-243X

DOI - 10.1063/1.3569513

Subject(s) - ribosome , stochastic process , statistical physics , translation (biology) , messenger rna , lattice (music) , process (computing) , asymmetric simple exclusion process , computer science , biological system , rna , physics , mathematics , biology , statistics , genetics , gene , acoustics , operating system

Translation is the cellular process in which ribosomes make proteins from information encoded on messenger RNA. We model this process using driven lattice gases and take into account the finite lifetime of mRNA. The stochastic properties of the translation process can then be determined from the time‐dependent current fluctuations of the lattice gas model. We illustrate our ideas with a totally asymmetric exclusion process with extended objects.

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