Open AccessRed Blood Cells Motion in a Glass Microchannel
Author(s) -
Diana Pinho,
Ana I. Pereira,
Rui Lima,
Theodore E. Simos,
George Psihoyios,
Ch. Tsitouras
Publication year - 2010
Publication title -
aip conference proceedings
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 0.177
H-Index - 75
eISSN - 1551-7616
pISSN - 0094-243X
DOI - 10.1063/1.3498656
Subject(s) - microchannel , microscale chemistry , hematocrit , microchannel plate detector , materials science , work (physics) , mechanics , motion (physics) , red blood cell , optics , chemistry , physics , classical mechanics , thermodynamics , mathematics , medicine , biochemistry , mathematics education , detector , endocrinology
The motion of the red blood cells (RBCs) flowing in microvessels and microchannels depend on several effects, such as hematocrit (Hct), geometry, and temperature. According to our knowledge, the effect of the temperature on RBC motion was never investigated at a microscale level. Hence, the aim of the present work is to determine the effect of the temperature on the RBC’s trajectories and to investigate the best approximation of the trajectories through a nonlinear optimization. In vitro human blood was pumped through a 100 μm circular microchannel and by using a confocal micro‐PTV system the RBC’s trajectories were measured at different temperatures, i.e., 25° C and 37° C. In this study we measured the motion of forty cells flowing in the middle of the microchannel and applied different functions to approximate its behavior.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom