Zirconia based nucleic acid sensor for Mycobacterium tuberculosis detection | Zendy

Maumita Das | Zendy; Gajjala Sumana | Zendy; R. Nagarajan | Zendy; Bansi D. Malhotra | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Zirconia based nucleic acid sensor for Mycobacterium tuberculosis detection

Author(s) -

Maumita Das,

Gajjala Sumana,

R. Nagarajan,

Bansi D. Malhotra

Publication year - 2010

Publication title -

applied physics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.182

H-Index - 442

eISSN - 1077-3118

pISSN - 0003-6951

DOI - 10.1063/1.3293447

Subject(s) - detection limit , biosensor , fourier transform infrared spectroscopy , materials science , cyclic voltammetry , scanning electron microscope , nuclear chemistry , zirconium , mycobacterium tuberculosis , cubic zirconia , analytical chemistry (journal) , chemistry , inorganic chemistry , nanotechnology , chemical engineering , electrochemistry , chromatography , tuberculosis , medicine , ceramic , electrode , composite material , pathology , engineering

Nanostructured zirconium oxide (ZrO2) film (particle size ∼ 35 nm), electrochemically deposited onto gold(Au) surface, has been used to immobilize 21-mer oligonucleotide probe (ssDNA) specific to Mycobacterium tuberculosis by utilizing affinity between oxygen atom of phosphoric group and zirconium to fabricate DNA biosensor. This DNA-ZrO2/Au bioelectrode, characterized using x-ray diffraction, Fourier transform infrared spectroscopy, cyclic voltammetry, and scanning electron microscopy techniques, can be used for early and rapid diagnosis of M. tuberculosis with detection limit of 0.065 ng/μL within 60s

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research