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Microcontroller-driven fluid-injection system for atomic force microscopy
Author(s) -
Sandor Kasas,
L. Alonso,
Patrick Jacquet,
Jozef Adamčík,
Christian Haeberli,
Giovanni Dietler
Publication year - 2010
Publication title -
review of scientific instruments
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.605
H-Index - 165
eISSN - 1089-7623
pISSN - 0034-6748
DOI - 10.1063/1.3285262
Subject(s) - microcontroller , materials science , atomic force microscopy , microscopy , process (computing) , computer science , nanotechnology , optics , computer hardware , physics , operating system
We present a programmable microcontroller-driven injection system for the exchange of imaging medium during atomic force microscopy. Using this low-noise system, high-resolution imaging can be performed during this process of injection without disturbance. This latter circumstance was exemplified by the online imaging of conformational changes in DNA molecules during the injection of anticancer drug into the fluid chamber.

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