Cerium oxide-chitosan based nanobiocomposite for food borne mycotoxin detection | Zendy

Ajeet Kaushik | Zendy; Pratima R. Solanki | Zendy; Manoj Kumar Pandey | Zendy; Sharif Ahmad | Zendy; Bansi D. Malhotra | Zendy

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Cerium oxide-chitosan based nanobiocomposite for food borne mycotoxin detection

Author(s) -

Ajeet Kaushik,

Pratima R. Solanki,

Manoj Kumar Pandey,

Sharif Ahmad,

Bansi D. Malhotra

Publication year - 2009

Publication title -

applied physics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.182

H-Index - 442

eISSN - 1077-3118

pISSN - 0003-6951

DOI - 10.1063/1.3249586

Subject(s) - detection limit , cerium oxide , indium tin oxide , chitosan , ochratoxin a , cerium , bovine serum albumin , substrate (aquarium) , nuclear chemistry , mycotoxin , chemistry , oxide , materials science , chromatography , nanotechnology , inorganic chemistry , thin film , organic chemistry , oceanography , food science , geology

Cerium oxide nanoparticles (NanoCeO2) and chitosan (CH) based nanobiocomposite film deposited onto indium-tin-oxide coated glass substrate has been used to coimmobilize rabbit immunoglobin (r-IgGs) and bovine serum albumin (BSA) for food borne mycotoxin [ochratoxin-A (OTA)] detection. Electrochemical studies reveal that presence of NanoCeO2 increases effective electro-active surface area of CH-NanoCeO2/indium tin oxide (ITO) nanobiocomposite resulting in high loading of r-IgGs. BSA/r-IgGs/CH-NanoCeO2/ITO immunoelectrode exhibits improved linearity (0.25–6.0 ng/dl), detection limit (0.25 ng/dl), response time (25 s), sensitivity (18 μA/ng dl−1 cm−2), and regression coefficient (r2 ∼ 0.997)

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