Nanostructured zinc oxide platform for cholesterol sensor | Zendy

Pratima R. Solanki | Zendy; Ajeet Kaushik | Zendy; Anees A. Ansari | Zendy; Bansi D. Malhotra | Zendy

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Nanostructured zinc oxide platform for cholesterol sensor

Author(s) -

Pratima R. Solanki,

Ajeet Kaushik,

Anees A. Ansari,

Bansi D. Malhotra

Publication year - 2009

Publication title -

applied physics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.182

H-Index - 442

eISSN - 1077-3118

pISSN - 0003-6951

DOI - 10.1063/1.3111429

Subject(s) - cholesterol oxidase , cyclic voltammetry , zinc , indium tin oxide , electrode , detection limit , crystallite , materials science , electrochemistry , oxide , analytical chemistry (journal) , nuclear chemistry , inorganic chemistry , chemistry , nanotechnology , thin film , metallurgy , cholesterol , chromatography , biochemistry

Nanostructured zinc oxide (nano-ZnO) film has been fabricated onto indium tin oxide (ITO) containing preferred (002) plane and 10 nm crystallite size using sol-gel technique for immobilization of cholesterol oxidase (ChOx). Electrochemical response of ChOx/nano-ZnO/ITO bioelectrode determined as a function of cholesterol concentration using cyclic voltammetry technique reveals improved detection range (5–400 mg/dl), low detection limit (0.5 mg/dl), fast response time (10 s), sensitivity (0.059 μA/mg dl−1 cm−2), and low value (0.98 mg/dl) of Michaelis–Menten constant (Km). It is shown that nano-ZnO film provides better environment and enhanced electron transfer between ChOx and electrode

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