High (1GHz) repetition rate compact femtosecond laser: A powerful multiphoton tool for nanomedicine and nanobiotechnology
Author(s) -
Alexander Ehlers,
Iris Riemann,
S. Martin,
Ronan Le Harzic,
A. Bartels,
C. Janke,
Karsten König
Publication year - 2007
Publication title -
journal of applied physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.699
H-Index - 319
eISSN - 1089-7550
pISSN - 0021-8979
DOI - 10.1063/1.2745367
Subject(s) - femtosecond , nanobiotechnology , laser , materials science , optics , multiphoton fluorescence microscope , microscopy , autofluorescence , tomography , microscope , optoelectronics , biomedical engineering , nanotechnology , fluorescence microscope , medicine , nanoparticle , physics , fluorescence
Multiphoton tomography of human skin and nanosurgery of human chromosomes have been performed with a 1 GHz repetition rate laser by the use of the commercially available femtosecond multiphoton laser tomograph DermaInspect as well as a compact galvoscanning microscope. We performed the autofluorescence tomography up to 100 mu m in the depth of human skin. Submicron cutting lines and hole drillings have been conducted on labeled human chromosomes
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