On-line laser photoacoustic detection of ethene in exhaled air as biomarker of ultraviolet radiation damage of the human skin | Zendy

Frans J. M. Harren | Zendy; R. Berkelmans | Zendy; KC Koen Kuiper | Zendy; S. te Lintel Hekkert | Zendy; Paul T.J. Scheepers | Zendy; R. Dekhuijzen | Zendy; Peter Hollander | Zendy; David H. Parker | Zendy

Open Access

On-line laser photoacoustic detection of ethene in exhaled air as biomarker of ultraviolet radiation damage of the human skin

Author(s) -

Frans J. M. Harren,

R. Berkelmans,

KC Koen Kuiper,

S. te Lintel Hekkert,

Paul T.J. Scheepers,

R. Dekhuijzen,

Peter Hollander,

David H. Parker

Publication year - 1999

Publication title -

applied physics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.182

H-Index - 442

eISSN - 1077-3118

pISSN - 0003-6951

DOI - 10.1063/1.123680

Subject(s) - exhaled air , ultraviolet , human skin , photoacoustic imaging in biomedicine , ultraviolet radiation , chemistry , irradiation , laser , materials science , biomarker , radiochemistry , optoelectronics , optics , toxicology , biochemistry , genetics , physics , biology , nuclear physics

The exhaled air and volatile emission by the skin of human subjects were analyzed for traces of ethene (C2H4) by means of CO2 laser photoacoustic trace gas detection. Due to the extreme sensitivity of the detection system (6 part per trillion volume, 6:1012), these measurements could be performed on-line and noninvasively. Exhaled ethene was used as a biomarker for lipid peroxidation in the skin of human subjects exposed to ultraviolet (UV) radiation from a solarium. A change in the ethene concentration was already observed in the exhaled air after 2 min. Adaptation of the skin to UV exposure and direct skin emission could also be observed.

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