Mycophenolate Mofetil for First-Line Treatment of Immune Thrombocytopenia
Author(s) -
Charlotte Bradbury,
Julie Pell,
Quentin A. Hill,
Catherine Bagot,
Nichola Cooper,
Jenny Ingram,
Katie Breheny,
Rebecca Kandiyali,
Rachel Rayment,
Gillian Evans,
Kate Talks,
Ian Thomas,
Rosemary Greenwood
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2100596
Subject(s) - medicine , adverse effect , hazard ratio , mycophenolate , glucocorticoid , gastroenterology , randomization , platelet , liter , randomized controlled trial , immune thrombocytopenia , surgery , confidence interval , transplantation
Immune thrombocytopenia is a rare autoimmune disorder with associated bleeding risk and fatigue. Recommended first-line treatment for immune thrombocytopenia is high-dose glucocorticoids, but side effects, variable responses, and high relapse rates are serious drawbacks.
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