Trial of Pimavanserin in Dementia-Related Psychosis
Author(s) -
Pierre N. Tariot,
Jeffrey L. Cummings,
María Soto-Martín,
Clive Ballard,
Deniz ErtenLyons,
David L. Sultzer,
Davangere P. Devanand,
Daniel Weintraub,
Bradley McEvoy,
James M. Youakim,
Srdjan Stankovic,
Erin P. Foff
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2034634
Subject(s) - dementia , psychosis , dementia with lewy bodies , antipsychotic , discontinuation , clinical global impression , vascular dementia , psychology , psychiatry , placebo , medicine , disease , schizophrenia (object oriented programming) , pathology , alternative medicine
Patients with dementia due to neurodegenerative disease can have dementia-related psychosis. The effects of the oral 5-HT 2A inverse agonist and antagonist pimavanserin on psychosis related to various causes of dementia are not clear.
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