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Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19
Author(s) -
Michael J. Joyner,
Rickey E. Carter,
Jonathon W. Senefeld,
Stephen A. Klassen,
John R. Mills,
Patrick W. Johnson,
Elitza S. Theel,
Chad C. Wiggins,
Katelyn A. Bruno,
Allan M. Klompas,
Elizabeth R. Lesser,
Katie L. Kunze,
Matthew A. Sexton,
Juan C. Diaz Soto,
Sarah E. Baker,
John R.A. Shepherd,
Noud van Helmond,
Nicole Verdun,
Peter Marks,
Camille M. van Buskirk,
Jeffrey L. Winters,
James R. Stubbs,
Robert F. Rea,
David O. Hodge,
Vitaly Herasevich,
Emily R. Whelan,
Andrew J. Clayburn,
Kathryn F. Larson,
Juan G. Ripoll,
Kylie J. Andersen,
Matthew Buras,
Matthew N.P. Vogt,
Joshua J. Dennis,
Riley J. Regimbal,
Philippe R. Bauer,
Janis E. Blair,
Nigel Paneth,
DeLisa Fairweather,
R. Scott Wright,
Arturo Casadevall
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2031893
Subject(s) - convalescent plasma , covid-19 , virology , antibody , medicine , immunology , outbreak , disease , infectious disease (medical specialty)
Convalescent plasma has been widely used to treat coronavirus disease 2019 (Covid-19) under the presumption that such plasma contains potentially therapeutic antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that can be passively transferred to the plasma recipient. Whether convalescent plasma with high antibody levels rather than low antibody levels is associated with a lower risk of death is unknown.

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