Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure
Author(s) -
Milton Packer,
Stefan D. Anker,
Javed Butler,
Gerasimos Filippatos,
Stuart J. Pocock,
Peter E. Carson,
James L. Januzzi,
Subodh Verma,
Hiroyuki Tsutsui,
Martina Brueckmann,
Waheed Jamal,
Karen Kimura,
Janet Schnee,
Cordula Zeller,
Daniel Cotton,
Edimar Alcides Bocchi,
Michael Böhm,
DongJu Choi,
Vijay Chopra,
Eduardo ChuquiureValenzuela,
Nadia Giannetti,
Stefan Janssens,
Jian Zhang,
José Ramón González–Juanatey,
Sanjay Kaul,
HansPeter BrunnerLa Rocca,
Béla Merkely,
Stephen J. Nicholls,
Sergio V. Perrone,
Ileana L. Piña,
Piotr Ponikowski,
Naveed Sattar,
Michele Senni,
MarieFrance Seronde,
Jindřich Špinar,
Iain Squire,
Stefano Taddei,
Christoph Wanner,
Faı̈ez Zannad
Publication year - 2020
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2022190
Subject(s) - empagliflozin , heart failure , medicine , ejection fraction , cardiology , diabetes mellitus , benzhydryl compounds , broad spectrum , heart failure with preserved ejection fraction , type 2 diabetes , endocrinology , chemistry , organic chemistry , bisphenol a , epoxy , combinatorial chemistry
Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure in patients regardless of the presence or absence of diabetes. More evidence is needed regarding the effects of these drugs in patients across the broad spectrum of heart failure, including those with a markedly reduced ejection fraction.
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