A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19
Author(s) -
David R. Boulware,
Matthew F Pullen,
Ananta Bangdiwala,
Katelyn A Pastick,
Sarah M Lofgren,
Elizabeth C Okafor,
Caleb P Skipper,
Alanna A Nascene,
Melanie R. Nicol,
Mahsa Abassi,
Nicole Engen,
Matthew P. Cheng,
Derek LaBar,
Sylvain Lother,
Lauren MacKenzie,
Glen Drobot,
Nicole Marten,
Ryan Zarychanski,
Lauren E. Kelly,
Ilan S. Schwartz,
Emily G. McDonald,
Radha Rajasingham,
Todd C. Lee,
Kathy Huppler Hullsiek
Publication year - 2020
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2016638
Subject(s) - hydroxychloroquine , medicine , placebo , asymptomatic , face shield , pre exposure prophylaxis , randomized controlled trial , covid-19 , confidence interval , incidence (geometry) , disease , virology , pathology , health care , human immunodeficiency virus (hiv) , men who have sex with men , physics , alternative medicine , syphilis , infectious disease (medical specialty) , optics , economics , economic growth
Coronavirus disease 2019 (Covid-19) occurs after exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For persons who are exposed, the standard of care is observation and quarantine. Whether hydroxychloroquine can prevent symptomatic infection after SARS-CoV-2 exposure is unknown.
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