Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy
Author(s) -
Ayman AlHendy,
Andrea S. Lukes,
Alfred N. Poindexter,
Roberta Venturella,
Claudio Villarroel,
Hilary Critchley,
Yulan Li,
Laura McKain,
Juan Camilo Arjona Ferreira,
Andria Langenberg,
Rachel B. Wagman,
Elizabeth A. Stewart
Publication year - 2021
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2008283
Subject(s) - uterine fibroids , medicine , ulipristal acetate , gynecology , menstrual bleeding , menstrual cycle , hormone antagonist , antagonist , uterine bleeding , hormone , obstetrics , research methodology , receptor , family planning , population , environmental health
Uterine fibroids are a common cause of heavy menstrual bleeding and pain. Treatment with the combination of relugolix (an oral gonadotropin-releasing hormone-receptor antagonist), estradiol, and norethindrone acetate, administered once daily, may have efficacy in women with uterine fibroids and heavy bleeding while avoiding hypoestrogenic effects.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom