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Compassionate Use of Remdesivir for Patients with Severe Covid-19
Author(s) -
Jonathan Grein,
Norio Ohmagari,
Daniel D. Shin,
George Diaz,
Erika Asperges,
Antonella Castagna,
Torsten Feldt,
Gary Green,
Margaret L. Green,
François-Xavier Lescure,
Emanuele Nicastri,
Rentaro Oda,
Kikuo Yo,
Eugenia Quirós-Roldán,
Alex Studemeister,
John Redinski,
Seema Ahmed,
Jorge R Bernett,
Daniel Chelliah,
Danny Chen,
Shingo Chihara,
Stuart H. Cohen,
Jennifer Cunningham,
Antonella d’Arminio Monforte,
Saad Ismail,
Hideaki Kato,
Giuseppe Lapadula,
Erwan L’Her,
Toshitaka Maeno,
Sumit Majumder,
Marco Massari,
Marta Mora-Rillo,
Yoshikazu Mutoh,
Duc Nguyen,
E. Verweij,
Alexander Zoufaly,
Anu Osinusi,
Adam DeZure,
Yang Zhao,
Lijie Zhong,
Anand P. Chokkalingam,
Emon Elboudwarej,
Laura Telep,
Leighann Timbs,
Ila. Henne,
Scott Sellers,
Huyen Cao,
Susanna K. Tan,
Lucinda Winterbourne,
Polly Desai,
Robertino M. Mera,
Anuj Gaggar,
Robert P. Myers,
Diana M. Brainard,
Richard W. Childs,
Timothy Flanigan
Publication year - 2020
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa2007016
Subject(s) - covid-19 , betacoronavirus , compassionate use , virology , medicine , coronavirus infections , coronavirus , outbreak , infectious disease (medical specialty) , disease , clinical trial
In this cohort of patients hospitalized for severe Covid-19 who were treated with compassionate-use remdesivir, clinical improvement was observed in 36 of 53 patients (68%). Measurement of efficacy will require ongoing randomized, placebo-controlled trials of remdesivir therapy. (Funded by Gilead Sciences.).

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