Tau Positron-Emission Tomography in Former National Football League Players
Author(s) -
Robert A. Stern,
Charles H. Adler,
Kewei Chen,
Michael Navitsky,
Ji Luo,
David W. Dodick,
Michael L. Alosco,
Yorghos Tripodis,
Dhruman D. Goradia,
Brett Martin,
Diego Mastroeni,
Nathan G. Fritts,
Johnny Jarnagin,
Michael D. Devous,
Mark A. Mintun,
Michael J. Pontecorvo,
Martha E. Shenton,
Eric M. Reiman
Publication year - 2019
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1900757
Subject(s) - chronic traumatic encephalopathy , standardized uptake value , positron emission tomography , asymptomatic , concussion , medicine , nuclear medicine , psychology , confidence interval , poison control , injury prevention , environmental health
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that has been associated with a history of repetitive head impacts. The neuropathological diagnosis is based on a specific pattern of tau deposition with minimal amyloid-beta deposition that differs from other disorders, including Alzheimer's disease. The feasibility of detecting tau and amyloid deposition in the brains of living persons at risk for CTE has not been well studied.
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