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Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions
Author(s) -
Kirsten Fischer,
Othman AlSawaf,
Jasmin Bahlo,
Anna-Maria Fink,
Maneesh Tandon,
Mark Dixon,
Sandra Robrecht,
Simon Warburton,
Kathryn Humphrey,
Olga Samoylova,
A. M. Liberati,
Javier PinillaIbarz,
Stephen Opat,
Liliya Sivcheva,
Katell Le Dû,
Laura Fogliatto,
Carsten Utoft Niemann,
Robert Weinkove,
Sue Robinson,
Thomas J. Kipps,
Sebastian Böettcher,
Eugen Tausch,
Rod Humerickhouse,
Barbara Eichhorst,
ClemensMartin Wendtner,
Anton W. Langerak,
Karl-Anton Kreuzer,
Matthias Ritgen,
Valentin Goede,
Stephan Stilgenbauer,
Mehrdad Mobasher,
Michael Hallek
Publication year - 2019
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1815281
Subject(s) - obinutuzumab , venetoclax , chlorambucil , medicine , ighv@ , regimen , hazard ratio , chronic lymphocytic leukemia , oncology , gastroenterology , surgery , confidence interval , leukemia , chemotherapy , cyclophosphamide
The BCL2 inhibitor venetoclax has shown activity in patients with chronic lymphocytic leukemia (CLL), but its efficacy in combination with other agents in patients with CLL and coexisting conditions is not known.

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