Open AccessHydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa
Author(s) -
Léon Tshilolo,
George Tomlinson,
Thomas N. Williams,
Brígida Santos,
Peter OlupotOlupot,
Adam Lane,
Banu Aygün,
Susan E. Stuber,
Teresa S. Latham,
Patrick T. McGann,
Russell E. Ware
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1813598
Subject(s) - sickle cell anemia , anemia , medicine , cell , pediatrics , biology , genetics
Hydroxyurea is an effective treatment for sickle cell anemia, but few studies have been conducted in sub-Saharan Africa, where the burden is greatest. Coexisting conditions such as malnutrition and malaria may affect the feasibility, safety, and benefits of hydroxyurea in low-resource settings.
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