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Effect of Aspirin on All-Cause Mortality in the Healthy Elderly
Author(s) -
John J. McNeil,
Mark Nelson,
Robyn L. Woods,
Jessica E. Lockery,
Rory Wolfe,
Christopher M. Reid,
Brenda Kirpach,
Raj C. Shah,
Diane G. Ives,
Elsdon Storey,
Joanne Ryan,
Andrew Tonkin,
Anne B. Newman,
Jeff D. Williamson,
Karen L. Margolis,
Michael E. Ernst,
Walter P. Abhayaratna,
Nigel Stocks,
Sharyn M. Fitzgerald,
Suzanne G. Orchard,
Ruth E. Trevaks,
Lawrence J. Beilin,
Geoffrey A. Donnan,
Peter Gibbs,
Colin I. Johnston,
Barbara Radziszewska,
Richard H. Grimm,
Anne M. Murray
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1803955
Subject(s) - aspirin , placebo , medicine , clinical endpoint , end point , cause of death , gerontology , randomized controlled trial , alternative medicine , disease , pathology , geometry , mathematics
In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not provide a benefit with regard to the primary end point of disability-free survival among older adults. A numerically higher rate of the secondary end point of death from any cause was observed with aspirin than with placebo.

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