Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection | Zendy

Nicholas J. Steers | Zendy; Yifu Li | Zendy; Zahida Drače | Zendy; Justin A. D’Addario | Zendy; Clara Fischman | Zendy; Lili Liu | Zendy; Katherine Xu | Zendy; Young-Ji Na | Zendy; Y. Daeugut | Zendy; Jun Y. Zhang | Zendy; Roel Sterken | Zendy; Olivia Balderes | Zendy; Drew Bradbury | Zendy; Nilgün Kavrut Öztürk | Zendy; Fatih Ozay | Zendy; Sanya Goswami | Zendy; Karla Mehl | Zendy; Jaclyn Wold | Zendy; Fatima Zahra Jelloul | Zendy; Mersedeh Rohanizadegan | Zendy; Christopher E. Gillies | Zendy; Elena-Rodica M. Vasilescu | Zendy; George Vlad | Zendy; Yi-An Ko | Zendy; Sumit Mohan | Zendy; Jai Radhakrishnan | Zendy; David J. Cohen | Zendy; Lloyd E. Ratner | Zendy; Francesco Scolari | Zendy; Katalin Suszták | Zendy; Matthew G. Sampson | Zendy; Silvia Deaglio | Zendy; Yaşar Çalışkan | Zendy; Jonathan Barasch | Zendy; Aisling E. Courtney | Zendy; Alexander P. Maxwell | Zendy; Amy Jayne McKnight | Zendy; Iuliana IonitaLaza | Zendy; Stephan J. L. Bakker | Zendy; Harold Snieder | Zendy; Martin H. de Borst | Zendy; Vivette D. D’Agati | Zendy; Antonio Amoroso | Zendy; Ali G. Gharavi | Zendy; Krzysztof Kiryluk | Zendy

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Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection

Author(s) -

Nicholas J. Steers,

Yifu Li,

Zahida Drače,

Justin A. D’Addario,

Clara Fischman,

Lili Liu,

Katherine Xu,

Young-Ji Na,

Y. Daeugut,

Jun Y. Zhang,

Roel Sterken,

Olivia Balderes,

Drew Bradbury,

Nilgün Kavrut Öztürk,

Fatih Ozay,

Sanya Goswami,

Karla Mehl,

Jaclyn Wold,

Fatima Zahra Jelloul,

Mersedeh Rohanizadegan,

Christopher E. Gillies,

Elena-Rodica M. Vasilescu,

George Vlad,

Yi-An Ko,

Sumit Mohan,

Jai Radhakrishnan,

David J. Cohen,

Lloyd E. Ratner,

Francesco Scolari,

Katalin Suszták,

Matthew G. Sampson,

Silvia Deaglio,

Yaşar Çalışkan,

Jonathan Barasch,

Aisling E. Courtney,

Alexander P. Maxwell,

Amy Jayne McKnight,

Iuliana IonitaLaza,

Stephan J. L. Bakker,

Harold Snieder,

Martin H. de Borst,

Vivette D. D’Agati,

Antonio Amoroso,

Ali G. Gharavi,

Krzysztof Kiryluk

Publication year - 2019

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1803731

Subject(s) - locus (genetics) , genetics , context (archaeology) , kidney transplantation , biology , gene , inheritance (genetic algorithm) , kidney , paleontology

In the context of kidney transplantation, genomic incompatibilities between donor and recipient may lead to allosensitization against new antigens. We hypothesized that recessive inheritance of gene-disrupting variants may represent a risk factor for allograft rejection.

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