Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma
Author(s) -
Arnaud Méjean,
Alain Ravaud,
Simon Thézenas,
Sandra Colas,
JeanBaptiste Beauval,
Karim Bensalah,
Lionnel Geoffrois,
Antoine Thiery-Vuillemin,
Laurent Cormier,
Hervé Lang,
Laurent Guy,
Gwénaëlle Gravis,
Frédéric Rolland,
Claude Linassier,
É. Lechevallier,
Christian Beisland,
Michael Aitchison,
Stéphane Oudard,
JeanJacques Patard,
C Théodore,
Christine Chevreau,
Brigitte Laguerre,
Jacques Hubert,
Marine GrossGoupil,
JeanChristophe Bernhard,
Laurence Albigès,
M.-O. Timsit,
Thierry Lebrét,
Bernard Escudier
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1803675
Subject(s) - sunitinib , renal cell carcinoma , nephrectomy , medicine , urology , oncology , kidney
Cytoreductive nephrectomy has been the standard of care in metastatic renal-cell carcinoma for 20 years, supported by randomized trials and large, retrospective studies. However, the efficacy of targeted therapies has challenged this standard. We assessed the role of nephrectomy in patients with metastatic renal-cell carcinoma who were receiving targeted therapies.
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