Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke | Zendy

Bruce Campbell | Zendy; Peter Mitchell | Zendy; Leonid Churilov | Zendy; Nawaf Yassi | Zendy; Timothy Kleinig | Zendy; Richard Dowling | Zendy; Bernard Yan | Zendy; Steven Bush | Zendy; Helen M. Dewey | Zendy; Vincent Thijs | Zendy; Rebecca Scroop | Zendy; Marion Simpson | Zendy; Mark Brooks | Zendy; Hamed Asadi | Zendy; Teddy Y. Wu | Zendy; Darshan Shah | Zendy; Tissa Wijeratne | Zendy; Timothy Ang | Zendy; Ferdinand Miteff | Zendy; Christopher Levi | Zendy; Edrich Rodrigues | Zendy; Henry Zhao | Zendy; Patrick Salvaris | Zendy; Carlos García-Esperón | Zendy; Peter Bailey | Zendy; Henry E. Rice | Zendy; Laetitia de Villiers | Zendy; Helen Brown | Zendy; Kendal Redmond | Zendy; David Leggett | Zendy; John Fink | Zendy; Wayne Collecutt | Zendy; Andrew Wong | Zendy; Claire Muller | Zendy; Alan Coulthard | Zendy; Ken Mitchell | Zendy; John Clouston | Zendy; Kate Mahady | Zendy; Deborah Field | Zendy; Henry Ma | Zendy; Thanh G. Phan | Zendy; Winston Chong | Zendy; Ronil V. Chandra | Zendy; LeeAnne Slater | Zendy; Martín Krause | Zendy; Timothy Harrington | Zendy; Kenneth Faulder | Zendy; Brendan Steinfort | Zendy; Christopher F. Bladin | Zendy; Gagan Sharma | Zendy; Patricia Desmond | Zendy; Mark Parsons | Zendy; Geoffrey A. Donnan | Zendy; Stephen M. Davis | Zendy

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Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke

Author(s) -

Bruce Campbell,

Peter Mitchell,

Leonid Churilov,

Nawaf Yassi,

Timothy Kleinig,

Richard Dowling,

Bernard Yan,

Steven Bush,

Helen M. Dewey,

Vincent Thijs,

Rebecca Scroop,

Marion Simpson,

Mark Brooks,

Hamed Asadi,

Teddy Y. Wu,

Darshan Shah,

Tissa Wijeratne,

Timothy Ang,

Ferdinand Miteff,

Christopher Levi,

Edrich Rodrigues,

Henry Zhao,

Patrick Salvaris,

Carlos García-Esperón,

Peter Bailey,

Henry E. Rice,

Laetitia de Villiers,

Helen Brown,

Kendal Redmond,

David Leggett,

John Fink,

Wayne Collecutt,

Andrew Wong,

Claire Muller,

Alan Coulthard,

Ken Mitchell,

John Clouston,

Kate Mahady,

Deborah Field,

Henry Ma,

Thanh G. Phan,

Winston Chong,

Ronil V. Chandra,

LeeAnne Slater,

Martín Krause,

Timothy Harrington,

Kenneth Faulder,

Brendan Steinfort,

Christopher F. Bladin,

Gagan Sharma,

Patricia Desmond,

Mark Parsons,

Geoffrey A. Donnan,

Stephen M. Davis

Publication year - 2018

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1716405

Subject(s) - medicine , tenecteplase , modified rankin scale , thrombolysis , fibrinolytic agent , stroke (engine) , intracerebral hemorrhage , tissue plasminogen activator , confidence interval , anesthesia , surgery , ischemia , subarachnoid hemorrhage , ischemic stroke , myocardial infarction , mechanical engineering , engineering

Intravenous infusion of alteplase is used for thrombolysis before endovascular thrombectomy for ischemic stroke. Tenecteplase, which is more fibrin-specific and has longer activity than alteplase, is given as a bolus and may increase the incidence of vascular reperfusion.

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