Neoadjuvant PD-1 Blockade in Resectable Lung Cancer
Author(s) -
Patrick M. Forde,
Jamie E. Chaft,
Kellie N. Smith,
Valsamo Anagnostou,
Tricia R. Cottrell,
Matthew D. Hellmann,
Marianna Zahurak,
Stephen C. Yang,
David R. Jones,
Stephen Broderick,
Richard J. Battafarano,
Moises J. Velez,
Natasha Rekhtman,
Zachary T. Olah,
Jarushka Naidoo,
Kristen A. Marrone,
Franco Verde,
Haidan Guo,
Jiajia Zhang,
Justina X. Caushi,
Hok Yee Chan,
John-William Sidhom,
Robert B. Scharpf,
James R. White,
Edward Gabrielson,
Hao Wang,
Gary L. Rosner,
Valerie W. Rusch,
Jedd D. Wolchok,
Taha Merghoub,
Janis M. Taube,
Victor E. Velculescu,
Suzanne L. Topalian,
Julie R. Brahmer,
Drew M. Pardoll
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1716078
Subject(s) - blockade , medicine , lung cancer , neoadjuvant therapy , oncology , cancer , receptor , breast cancer
Antibodies that block programmed death 1 (PD-1) protein improve survival in patients with advanced non-small-cell lung cancer (NSCLC) but have not been tested in resectable NSCLC, a condition in which little progress has been made during the past decade.
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