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Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer
Author(s) -
Matthew R. Smith,
Fred Saad,
Simon Chowdhury,
Stéphane Oudard,
Boris Hadaschik,
Julie N. Graff,
David Olmos,
Paul N. Mainwaring,
Ji Youl Lee,
Hiroji Uemura,
Angela LopezGitlitz,
Géralyn C. Trudel,
Byron M. Espina,
Youyi Shu,
Youn C. Park,
Wayne Rackoff,
Margaret K. Yu,
Eric J. Small
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1715546
Subject(s) - prostate cancer , cancer , metastasis , oncology , medicine , prostate
Apalutamide, a competitive inhibitor of the androgen receptor, is under development for the treatment of prostate cancer. We evaluated the efficacy of apalutamide in men with nonmetastatic castration-resistant prostate cancer who were at high risk for the development of metastasis.

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