Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations
Author(s) -
Daniel J. Jackson,
Leonard B. Bacharier,
David T. Mauger,
Susan Boehmer,
Avraham Beigelman,
James F. Chmiel,
Anne M. Fitzpatrick,
Jonathan M. Gaffin,
Wayne J. Morgan,
Stephen P. Peters,
Wanda Phipatanakul,
William J. Sheehan,
Michael D. Cabana,
Fernando Holguín,
Fernando D. Martínez,
Jacqueline A. Pongracic,
Sachin N. Baxi,
Mindy Benson,
Kathryn Blake,
Ronina Covar,
Deborah A. Gentile,
Elliot Israel,
Jerry A. Krishnan,
Harsha Kumar,
Jason E. Lang,
Stephen C. Lazarus,
John J. Lima,
Dayna Long,
Ngoc P. Ly,
Jyothi Marbin,
James N. Moy,
Ross Myers,
J. Tod Olin,
Hengameh H. Raissy,
Rachel G. Robison,
Kristie Ross,
Christine A. Sorkness,
Robert F. Lemanske
Publication year - 2018
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1710988
Subject(s) - medicine , asthma , inhaled corticosteroids , asthma exacerbations , intensive care medicine , pediatrics , immunology
Asthma exacerbations occur frequently despite the regular use of asthma-controller therapies, such as inhaled glucocorticoids. Clinicians commonly increase the doses of inhaled glucocorticoids at early signs of loss of asthma control. However, data on the safety and efficacy of this strategy in children are limited.
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