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Oral versus Intravenous Antibiotics for Bone and Joint Infection
Author(s) -
Ho Kwong Li,
Ines Rombach,
Rhea Zambellas,
A. Sarah Walker,
Martin McNally,
Bridget L. Atkins,
Benjamin A. Lipsky,
Harriet Hughes,
Deepa Bose,
Michelle Kümin,
Claire Scarborough,
Philippa C. Matthews,
Andrew Brent,
José Manuel Lomas,
Roger Gundle,
M. Rogers,
Adrian Taylor,
Brian Angus,
Ivor Byren,
Anthony R. Berendt,
Simon Warren,
Fiona E. Fitzgerald,
Damien Mack,
Susan Hopkins,
Jonathan Folb,
Helen Reynolds,
Elinor Moore,
Jocelyn R. Marshall,
Neil Jenkins,
Christopher E. Moran,
Andrew Woodhouse,
Samantha Stafford,
R.A. Seaton,
Claire Vallance,
Carolyn Hemsley,
Karen Bisnauthsing,
Jonathan Sandoe,
Ila Aggarwal,
Simon Ellis,
Deborah Bunn,
Rebecca Sutherland,
Gavin Barlow,
Cushla Cooper,
Claudia Geue,
Nicola McMeekin,
Andrew Briggs,
Parham Sendi,
Elham Khatamzas,
Tri Wangrangsimakul,
T.H. Nicholas Wong,
Lucinda Barrett,
Abtin Alvand,
ChristopherW. Old,
Jennifer Bostock,
John R. Paul,
Graham Cooke,
Guy Thwaites,
Philip Bejon,
Matthew Scarborough
Publication year - 2019
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1710926
Subject(s) - antibiotics , medicine , intravenous therapy , intravenous antibiotics , joint infections , orthopedic surgery , antibiotic therapy , intensive care medicine , surgery , arthroplasty , microbiology and biotechnology , biology , periprosthetic
The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is noninferior to intravenous antibiotic therapy for this indication.

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