Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer | Zendy

Willemien J. van Driel | Zendy; Simone N. Koole | Zendy; Karolina Sikorska | Zendy; Jules H. Schagen van Leeuwen | Zendy; Henk W.R. Schreuder | Zendy; Ralph H.M. Hermans | Zendy; Ignace H. J. T. de Hingh | Zendy; Jacobus van der Velden | Zendy; Henriëtte J.G. Arts | Zendy; Leon F.A.G. Massuger | Zendy; Arend G. J. Aalbers | Zendy; Victor J. Verwaal | Zendy; Jacobien M. Kieffer | Zendy; Koen Van de Vijver | Zendy; Harm van Tinteren | Zendy; Neil K. Aaronson | Zendy; Gabe S. Sonke | Zendy

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Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

Author(s) -

Willemien J. van Driel,

Simone N. Koole,

Karolina Sikorska,

Jules H. Schagen van Leeuwen,

Henk W.R. Schreuder,

Ralph H.M. Hermans,

Ignace H. J. T. de Hingh,

Jacobus van der Velden,

Henriëtte J.G. Arts,

Leon F.A.G. Massuger,

Arend G. J. Aalbers,

Victor J. Verwaal,

Jacobien M. Kieffer,

Koen Van de Vijver,

Harm van Tinteren,

Neil K. Aaronson,

Gabe S. Sonke

Publication year - 2018

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1708618

Subject(s) - medicine , hyperthermic intraperitoneal chemotherapy , surgery , carboplatin , hazard ratio , ovarian cancer , cytoreductive surgery , chemotherapy , cisplatin , confidence interval , cancer

Treatment of newly diagnosed advanced-stage ovarian cancer typically involves cytoreductive surgery and systemic chemotherapy. We conducted a trial to investigate whether the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery would improve outcomes among patients who were receiving neoadjuvant chemotherapy for stage III epithelial ovarian cancer.

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