Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease | Zendy

Paul M. Ridker | Zendy; Giulia Renda | Zendy; Tom Thurén | Zendy; Jean MacFadyen | Zendy; William H. Chang | Zendy; Christie M. Ballantyne | Zendy; Francisco Antônio Helfenstein Fonseca | Zendy; José Carlos Nicolau | Zendy; Wolfgang Köenig | Zendy; Stefan D. Anker | Zendy; John J.P. Kastelein | Zendy; Jan H. Cornel | Zendy; Prem Pais | Zendy; Daniel Pella | Zendy; Jacques Genest | Zendy; Renata Cífková | Zendy; Alberto J. Lorenzatti | Zendy; Tamás Forster | Zendy; Zhanna Kobalava | Zendy; L Vida-Simiti | Zendy; Marcus Flather | Zendy; Hiroaki Shimokawa | Zendy; Hisao Ogawa | Zendy; Mikael Dellborg | Zendy; Paulo R.F. Rossi | Zendy; Roland P.T. Troquay | Zendy; Peter Libby | Zendy; Robert J. Glynn | Zendy

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Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Author(s) -

Paul M. Ridker,

Giulia Renda,

Tom Thurén,

Jean MacFadyen,

William H. Chang,

Christie M. Ballantyne,

Francisco Antônio Helfenstein Fonseca,

José Carlos Nicolau,

Wolfgang Köenig,

Stefan D. Anker,

John J.P. Kastelein,

Jan H. Cornel,

Prem Pais,

Daniel Pella,

Jacques Genest,

Renata Cífková,

Alberto J. Lorenzatti,

Tamás Forster,

Zhanna Kobalava,

L Vida-Simiti,

Marcus Flather,

Hiroaki Shimokawa,

Hisao Ogawa,

Mikael Dellborg,

Paulo R.F. Rossi,

Roland P.T. Troquay,

Peter Libby,

Robert J. Glynn

Publication year - 2017

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1707914

Subject(s) - canakinumab , medicine , placebo , myocardial infarction , hazard ratio , confidence interval , randomized controlled trial , clinical endpoint , c reactive protein , surgery , gastroenterology , inflammation , disease , pathology , anakinra , alternative medicine

Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved.

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