Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer
Author(s) -
Karim Fizazi,
NamPhuong Tran,
Luis Fein,
Nobuaki Matsubara,
A. Rodrı́guez-Antolı́n,
B. Yа. Alekseev,
Mustafa Özgüroğlu,
Dingwei Ye,
Susan Feyerabend,
Andrew Protheroe,
Peter De Porre,
Thian Kheoh,
Youn C. Park,
Mary B. Todd,
Kim N.
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1704174
Subject(s) - medicine , abiraterone acetate , prostate cancer , prednisone , hazard ratio , placebo , androgen deprivation therapy , interim analysis , urology , clinical endpoint , oncology , surgery , randomized controlled trial , cancer , confidence interval , pathology , alternative medicine
Abiraterone acetate, a drug that blocks endogenous androgen synthesis, plus prednisone is indicated for metastatic castration-resistant prostate cancer. We evaluated the clinical benefit of abiraterone acetate plus prednisone with androgen-deprivation therapy in patients with newly diagnosed, metastatic, castration-sensitive prostate cancer.
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