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Glecaprevir and Pibrentasvir in Patients with HCV and Severe Renal Impairment
Author(s) -
Edward Gane,
Eric Lawitz,
David Pugatch,
George Papatheodoridis,
Norbert Bräu,
Ashley Brown,
Stanislas Pol,
Vincent Leroy,
Marcello Persico,
Christophe Moreno,
Massimo Colombo,
Eric M. Yoshida,
David R. Nelson,
Christine A. Collins,
Lei Yang,
Matthew P. Kosloski,
Federico Mensa
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1704053
Subject(s) - medicine , kidney disease , disease , hepatitis c virus , chronic hepatitis , chronic infection , chronic renal disease , gastroenterology , immunology , virus , immune system
Chronic hepatitis C virus (HCV) infection is more prevalent among patients who have chronic kidney disease than among those who do not have the disease. Patients with chronic kidney disease who also have HCV infection are at higher risk for progression to end-stage renal disease than those who have chronic kidney disease without HCV infection. Patients with both HCV infection and advanced chronic kidney disease have limited treatment options.

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