Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy
Author(s) -
Nicholas D. James,
Johann S. de Bono,
Melissa Spears,
Noel W. Clarke,
Malcolm D. Mason,
David P. Dearnaley,
A.W.S. Ritchie,
Claire Amos,
Clare Gilson,
Robert J. Jones,
David Matheson,
Robin Millman,
Gerhardt Attard,
Simon Chowdhury,
William Cross,
Silke Gillessen,
Christopher Parker,
John M. Russell,
Dominik Berthold,
Christopher D. Brawley,
F. Adab,
San Aung,
Alison Birtle,
Jo Bowen,
Susannah Brock,
Prabir Chakraborti,
Catherine Ferguson,
Joanna Gale,
Emma Gray,
Mohan Hingorani,
Peter Hoskin,
J.F. Lester,
Zafar Malik,
Fiona McKinna,
Neil McPhail,
Julian MoneyKyrle,
Joe M. O’Sullivan,
Omi Parikh,
Andrew Protheroe,
Angus Robinson,
Narayanan Srihari,
Carys Thomas,
John Wagstaff,
James Wylie,
Anjali Zarkar,
Mahesh Parmar,
Matthew R. Sydes
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1702900
Subject(s) - abiraterone acetate , prostate cancer , abiraterone , androgen deprivation therapy , medicine , oncology , testosterone (patch) , cancer , prostate , hormone therapy , prednisolone , urology , androgen receptor , breast cancer
Abiraterone acetate plus prednisolone improves survival in men with relapsed prostate cancer. We assessed the effect of this combination in men starting long-term androgen-deprivation therapy (ADT), using a multigroup, multistage trial design.
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