Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation
Author(s) -
Hugh Calkins,
Stephan Willems,
Edward P. Gerstenfeld,
Atul Kumar,
Richard J. Schilling,
Stefan H. Hohnloser,
Ken Okumura,
Harvey Serota,
Matias Nordaby,
Kelly Guiver,
Branislav Biss,
Marc A. Brouwer,
Massimo Grimaldi
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1701005
Subject(s) - medicine , dabigatran , vitamin k antagonist , warfarin , atrial fibrillation , oral anticoagulant , catheter ablation , ablation , anesthesia , cardiology , anticoagulant , vitamin k epoxide reductase , antagonist , receptor , cyp2c9 , cytochrome p450 , metabolism
Catheter ablation of atrial fibrillation is typically performed with uninterrupted anticoagulation with warfarin or interrupted non-vitamin K antagonist oral anticoagulant therapy. Uninterrupted anticoagulation with a non-vitamin K antagonist oral anticoagulant, such as dabigatran, may be safer; however, controlled data are lacking. We investigated the safety of uninterrupted dabigatran versus warfarin in patients undergoing ablation of atrial fibrillation.
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