Open AccessTiotropium in Early-Stage Chronic Obstructive Pulmonary Disease
Author(s) -
Yumin Zhou,
Nanshan Zhong,
Xiaochen Li,
Shuyun Chen,
Jinping Zheng,
Dongxing Zhao,
Weimin Yao,
Rong-Chang Zhi,
Liping Wei,
HE Bingwen,
Xiangyan Zhang,
Changli Yang,
Ying Li,
Fenglei Li,
Juan Du,
Jianping Gui,
Bin Hu,
Chunxue Bai,
Ping Huang,
Gang Chen,
Yongjian Xu,
Changzheng Wang,
Biao Liang,
Yinhuan Li,
Guoping Hu,
Hui Jan Tan,
Xianwei Ye,
Xi-tao Ma,
Yan Chen,
Xiwei Hu,
Jia Tian,
Xiaodan Zhu,
Zhe Shi,
XiuFang Du,
Minjing Li,
Shengming Liu,
Ronghuan Yu,
Jianping Zhao,
Qianli Ma,
Canmao Xie,
Xiongbin Li,
Tao Chen,
Yingxiang Lin,
Li-zhen Zeng,
Changxiu Ye,
Weishu Ye,
Xiangwen Luo,
Lingshan Zeng,
Shuqing Yu,
Weijie Guan,
Pixin Ran
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1700228
Subject(s) - medicine , copd , pulmonary disease , lung function , stage (stratigraphy) , pulmonary function testing , obstructive lung disease , lung , tiotropium bromide , disease , intensive care medicine , paleontology , biology
Patients with mild or moderate chronic obstructive pulmonary disease (COPD) rarely receive medications, because they have few symptoms. We hypothesized that long-term use of tiotropium would improve lung function and ameliorate the decline in lung function in patients with mild or moderate COPD.
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