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Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI
Author(s) -
Matthias Götberg,
Evald Høj Christiansen,
Ingibjörg Guđmundsdóttir,
Lennart Sandhall,
Mikael Danielewicz,
Lars Jakobsen,
S. Bertil Olsson,
Patrik Öhagen,
Hans Olsson,
Elmir Ömerovic,
Fredrik Calais,
Pontus Lindroos,
Michael Mæng,
Tim Tödt,
Dimitrios Venetsanos,
Stefan James,
Amra Kåregren,
Margareta Nilsson,
J. Carlsson,
Dario Hauer,
Jens Jensen,
Ann-Charlotte Karlsson,
Georgios Panayi,
David Erlinge,
Ole Frøbert
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1616540
Subject(s) - medicine , fractional flow reserve , cardiology , hazard ratio , revascularization , confidence interval , clinical endpoint , myocardial infarction , conventional pci , angioplasty , unstable angina , rate ratio , randomized controlled trial , stenosis , coronary angiography
The instantaneous wave-free ratio (iFR) is an index used to assess the severity of coronary-artery stenosis. The index has been tested against fractional flow reserve (FFR) in small trials, and the two measures have been found to have similar diagnostic accuracy. However, studies of clinical outcomes associated with the use of iFR are lacking. We aimed to evaluate whether iFR is noninferior to FFR with respect to the rate of subsequent major adverse cardiac events.

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