Cluster-Randomized, Crossover Trial of Head Positioning in Acute Stroke
Author(s) -
Craig S. Anderson,
Hisatomi Arima,
Pablo M. Lavados,
Laurent Billot,
Maree L. Hackett,
Verónica V. Olavarría,
Paula Muñoz Venturelli,
Stephen Jan,
Bin Peng,
Liying Cui,
Lili Song,
Kris Rogers,
Sandy Middleton,
Joyce Lim,
Denise Forshaw,
Catherine Elizabeth Lightbody,
Mark Woodward,
Octávio Marques PontesNeto,
H. Asita De Silva,
RueyTay Lin,
TsongHai Lee,
Jeyaraj Pandian,
Gillian Mead,
Thompson Robinson,
Caroline L Watkins
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1615715
Subject(s) - medicine , supine position , sitting , interquartile range , stroke (engine) , crossover study , randomized controlled trial , confidence interval , modified rankin scale , randomization , odds ratio , thrombolysis , physical therapy , ischemic stroke , myocardial infarction , ischemia , mechanical engineering , alternative medicine , pathology , engineering , placebo
The role of supine positioning after acute stroke in improving cerebral blood flow and the countervailing risk of aspiration pneumonia have led to variation in head positioning in clinical practice. We wanted to determine whether outcomes in patients with acute ischemic stroke could be improved by positioning the patient to be lying flat (i.e., fully supine with the back horizontal and the face upwards) during treatment to increase cerebral perfusion.
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