Lithium Use in Pregnancy and the Risk of Cardiac Malformations
Author(s) -
Elisabetta Patorno,
Krista F. Huybrechts,
Brian T. Bateman,
Jacqueline M. Cohen,
Rishi Desai,
Helen Mogun,
Lee S. Cohen,
Sonia Hernández–Dı́az
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1612222
Subject(s) - pregnancy , medicine , lithium (medication) , congenital malformations , ventricular outflow tract , first trimester , early pregnancy factor , cardiology , fetus , obstetrics , gestation , genetics , biology
There has been concern that exposure to lithium early in pregnancy may be associated with a marked increase in the risk of Ebstein's anomaly (a right ventricular outflow tract obstruction defect) in infants and overall congenital cardiac defects, but data are conflicting and limited.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom