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Lithium Use in Pregnancy and the Risk of Cardiac Malformations
Author(s) -
Elisabetta Patorno,
Krista F. Huybrechts,
Brian T. Bateman,
Jacqueline M. Cohen,
Rishi Desai,
Helen Mogun,
Lee S. Cohen,
Sonia Hernández–Dı́az
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1612222
Subject(s) - pregnancy , medicine , lithium (medication) , congenital malformations , ventricular outflow tract , first trimester , early pregnancy factor , cardiology , fetus , obstetrics , gestation , genetics , biology
There has been concern that exposure to lithium early in pregnancy may be associated with a marked increase in the risk of Ebstein's anomaly (a right ventricular outflow tract obstruction defect) in infants and overall congenital cardiac defects, but data are conflicting and limited.

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