Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease
Author(s) -
William R. Hiatt,
F. Gerry R. Fowkes,
Gretchen Heizer,
Jeffrey S. Berger,
Iris Baumgärtner,
Peter Held,
Brian G. Katona,
Kenneth W. Mahaffey,
Lars Norgren,
W. Schuyler Jones,
Juuso Blomster,
Marcus Millegård,
Martin Craig,
Manesh R. Patel
Publication year - 2016
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1611688
Subject(s) - medicine , clopidogrel , ticagrelor , aspirin , peripheral , arterial disease , cardiology , adverse effect , coronary artery disease , disease , platelet aggregation inhibitor , vascular disease
Peripheral artery disease is considered to be a manifestation of systemic atherosclerosis with associated adverse cardiovascular and limb events. Data from previous trials have suggested that patients receiving clopidogrel monotherapy had a lower risk of cardiovascular events than those receiving aspirin. We wanted to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in patients with peripheral artery disease.
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