Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis | Zendy

Eric L. Simpson | Zendy; Thomas Bieber | Zendy; Emma GuttmanYassky | Zendy; Lisa A. Beck | Zendy; Andrew Blauvelt | Zendy; Michael J. Cork | Zendy; Jonathan I. Silverberg | Zendy; Mette Deleuran | Zendy; Yoko Kataoka | Zendy; J.P. Lacour | Zendy; Külli Kingo | Zendy; Margitta Worm | Zendy; Yves Poulin | Zendy; Andreas Wollenberg | Zendy; Yuhwen Soo | Zendy; Neil M.H. Graham | Zendy; Gianluca Pirozzi | Zendy; Bolanle Akinlade | Zendy; Heribert Staudinger | Zendy; Vera Mastey | Zendy; Laurent Eckert | Zendy; Abhijit Gadkari | Zendy; Neil Stahl | Zendy; George D. Yancopoulos | Zendy; Marius Ardeleanu | Zendy

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Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

Author(s) -

Eric L. Simpson,

Thomas Bieber,

Emma GuttmanYassky,

Lisa A. Beck,

Andrew Blauvelt,

Michael J. Cork,

Jonathan I. Silverberg,

Mette Deleuran,

Yoko Kataoka,

J.P. Lacour,

Külli Kingo,

Margitta Worm,

Yves Poulin,

Andreas Wollenberg,

Yuhwen Soo,

Neil M.H. Graham,

Gianluca Pirozzi,

Bolanle Akinlade,

Heribert Staudinger,

Vera Mastey,

Laurent Eckert,

Abhijit Gadkari,

Neil Stahl,

George D. Yancopoulos,

Marius Ardeleanu

Publication year - 2016

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1610020

Subject(s) - dupilumab , medicine , placebo , atopic dermatitis , eczema area and severity index , clinical endpoint , randomized controlled trial , placebo controlled study , scorad , gastroenterology , dermatology life quality index , dermatology , disease , double blind , pathology , alternative medicine

Dupilumab, a human monoclonal antibody against interleukin-4 receptor alpha, inhibits signaling of interleukin-4 and interleukin-13, type 2 cytokines that may be important drivers of atopic or allergic diseases such as atopic dermatitis.

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