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Declining Risk of Sudden Death in Heart Failure
Author(s) -
Li Shen,
Pardeep S. Jhund,
Mark C. Petrie,
Brian Claggett,
Simona Barlera,
John G.F. Cleland,
Henry J. Dargie,
Christopher B. Granger,
John Kjekshus,
Lars Køber,
Roberto Latini,
Aldo P. Maggioni,
Milton Packer,
Bertram Pitt,
Scott D. Solomon,
Karl Swedberg,
Luigi Tavazzi,
John Wikstrand,
Faı̈ez Zannad,
Michael R. Zile,
John J.V. McMurray
Publication year - 2017
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1609758
Subject(s) - medicine , heart failure , ejection fraction , sudden death , hazard ratio , sudden cardiac death , cardiology , proportional hazards model , randomization , myocardial infarction , cumulative incidence , clinical trial , cohort , confidence interval
The risk of sudden death has changed over time among patients with symptomatic heart failure and reduced ejection fraction with the sequential introduction of medications including angiotensin-converting-enzyme inhibitors, angiotensin-receptor blockers, beta-blockers, and mineralocorticoid-receptor antagonists. We sought to examine this trend in detail.

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